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B P Monia Selected Research

Antisense Oligonucleotides

6/2008Inhibition of spinal cytosolic phospholipase A(2) expression by an antisense oligonucleotide attenuates tissue injury-induced hyperalgesia.
10/2003Bcl-x(L) antisense oligonucleotides radiosensitise colon cancer cells.
11/2001Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer.
10/2001Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells.
9/2001Antitumor activity of antisense clusterin oligonucleotides is improved in vitro and in vivo by incorporation of 2'-O-(2-methoxy)ethyl chemistry.
5/2001Phase I Trial of ISIS 5132, an antisense oligonucleotide inhibitor of c-raf-1, administered by 24-hour weekly infusion to patients with advanced cancer.
10/2000Antisense inhibition of membrane-bound human interleukin-5 receptor-alpha chain does not affect soluble receptor expression and induces apoptosis in TF-1 cells.
6/2000STAT3 regulates the growth and immunoglobulin production of BCL(1) B cell lymphoma through control of cell cycle progression.
5/2000Inhibition of antigen-induced eosinophilia and late phase airway hyperresponsiveness by an IL-5 antisense oligonucleotide in mouse models of asthma.
5/2000Inhibition of hypoxia/reoxygenation-induced apoptosis by an antisense oligonucleotide targeted to JNK1 in human kidney cells.

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B P Monia Research Topics

Disease

8Neoplasms (Cancer)
11/2004 - 01/2000
3Eosinophilia
02/2001 - 05/2000
3Asthma (Bronchial Asthma)
10/2000 - 05/2000
2Prostatic Neoplasms (Prostate Cancer)
09/2001 - 04/2001
2Peritonitis
02/2001 - 05/2000
2Respiratory Hypersensitivity
10/2000 - 05/2000
1Thymoma (Thymic Carcinoma)
04/2011
1Insulin Resistance
04/2011
1Pain (Aches)
06/2008
1Hyperalgesia
06/2008
1Carcinogenesis
11/2004
1Colonic Neoplasms (Colon Cancer)
10/2003
1Ovarian Neoplasms (Ovarian Cancer)
11/2001
1Adenocarcinoma
10/2001
1Carcinoma (Carcinomatosis)
10/2001
1Infections
10/2001
1Hemolytic Anemia
05/2001
1Edema (Dropsy)
05/2001
1Acute Kidney Injury (Acute Renal Failure)
05/2001
1Reperfusion Injury
04/2001
1Ischemia
04/2001
1Inflammation (Inflammations)
08/2000
1Lymphoma (Lymphomas)
06/2000
1B-Cell Lymphoma (Lymphoma, B Cell)
06/2000
1Hypoxia (Hypoxemia)
05/2000
1Necrosis
05/2000

Drug/Important Bio-Agent (IBA)

10Antisense OligonucleotidesIBA
06/2008 - 05/2000
5Proteins (Proteins, Gene)FDA Link
11/2001 - 01/2000
3Messenger RNA (mRNA)IBA
06/2008 - 06/2000
3OligonucleotidesIBA
09/2001 - 05/2000
3Interleukin-5 (Interleukin 5)IBA
02/2001 - 05/2000
2Protein Isoforms (Isoforms)IBA
06/2008 - 04/2001
2Paclitaxel (Taxol)FDA LinkGeneric
09/2001 - 06/2000
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
04/2011
1Insulin (Novolin)FDA Link
04/2011
1EnzymesIBA
06/2008
1Formaldehyde (Formol)FDA Link
06/2008
1Phospholipases (Phospholipase)IBA
06/2008
1Nuclear Proteins (Protein, Nuclear)IBA
11/2004
1bcl-X ProteinIBA
10/2003
1Cisplatin (Platino)FDA LinkGeneric
10/2003
1Epidermal Growth Factor (EGF)IBA
10/2001
1Phosphotransferases (Kinase)IBA
10/2001
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
10/2001
1Focal Adhesion Protein-Tyrosine KinasesIBA
10/2001
1ClusterinIBA
09/2001
1ISIS 5132IBA
05/2001
1Telomerase (Telomerase Reverse Transcriptase)IBA
04/2001
1RibonucleoproteinsIBA
04/2001
1JNK Mitogen-Activated Protein KinasesIBA
04/2001
1Mitogen-Activated Protein Kinase 8IBA
04/2001
1Propidium (Propidium Iodide)IBA
04/2001
1Acridine OrangeIBA
04/2001
1Mitogen-Activated Protein Kinase 9IBA
04/2001
1Annexin A5IBA
04/2001
1Ethidium (Ethidium Bromide)IBA
04/2001
1Fluorescein (Funduscein)FDA LinkGeneric
04/2001
1InterleukinsIBA
02/2001
1CytokinesIBA
02/2001
1LigandsIBA
10/2000
1Therapeutic UsesIBA
08/2000
1Interleukin-5 Receptors (Interleukin 5 Receptor)IBA
08/2000
1RNA (Ribonucleic Acid)IBA
08/2000
1Cytokine Receptors (Cytokine Receptor)IBA
08/2000
1Serine (L-Serine)FDA Link
06/2000
1Immunoglobulins (Immunoglobulin)IBA
06/2000
1OligodeoxyribonucleotidesIBA
06/2000
1ElementsIBA
06/2000
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
06/2000
1AndrogensIBA
06/2000
1Immunoglobulin M (IgM)IBA
06/2000
1AllergensIBA
05/2000
1AntigensIBA
05/2000
1p38 Mitogen-Activated Protein KinasesIBA
05/2000
1Coloring Agents (Dyes)IBA
05/2000
1DNA (Deoxyribonucleic Acid)IBA
05/2000

Therapy/Procedure

4Drug Therapy (Chemotherapy)
10/2003 - 06/2000
2Therapeutics
11/2004 - 06/2000
2Castration
09/2001 - 06/2000
2Intravenous Administration
02/2001 - 05/2000
1Withholding Treatment
11/2004